Exploration of the advantages of biological buffer BICINE

In the fields of biochemistry and molecular biology, buffering agents are crucial for maintaining the stability of solution pH, as they are related to the activity and functional performance of biomolecules. BICINE， As a commonly used biological buffer, it has demonstrated significant advantages in numerous application scenarios due to its unique properties.

1、 Excellent buffering performance

（1） Suitable and broad pH buffering range

The pH buffer range of BICINE is between 7.6-9.0, which is close to the weak alkaline range in the physiological environment of organisms and meets the pH requirements of most biochemical reactions and biological processes. Taking enzymatic reactions as an example, most enzymes have the highest activity at a specific pH value. Beyond the appropriate range, enzyme activity will be inhibited or even inactivated. The BICINE buffer system can provide a stable weakly alkaline environment, ensuring the smooth progress of numerous enzyme catalyzed biochemical reactions. For example, in serum guanine enzyme assays, it accurately maintains the pH conditions required for the reaction, ensures enzyme activity stability, and makes detection results accurate and reliable.

（2） Powerful buffering capacity and stability

Faced with the addition of external acidic and alkaline substances or changes in acidity and alkalinity during the reaction process, BICINE, with its structural characteristics, can quickly respond and neutralize fluctuations in acidity and alkalinity, maintaining a relatively constant pH value of the solution. In protein electrophoresis experiments, as electrophoresis proceeds, an electrolytic reaction occurs at both ends of the electrode, causing a change in the pH value of the solution. BICINE buffer can effectively counteract this change, ensuring that protein molecules migrate in a stable pH environment, thereby obtaining clear and accurate electrophoresis patterns, greatly improving the reliability and reproducibility of experimental results.

2、Unique chelating properties

The specific functional groups in the BICINE molecular structure endow it with the ability to chelate metal ions to a certain extent. In the field of cosmetics, the ingredients are complex and may contain metal ions such as iron and copper, which can affect product stability and efficacy, and even irritate the skin. BICINE can chelate with these metal ions to form stable complexes, reducing the adverse effects of metal ions on cosmetics, such as preventing metal ion catalyzed oxidation reactions and extending product shelf life; Reduce the irritation of metal ions to the skin and enhance the safety and mildness of the product. In terms of soil remediation, BICINE can specifically chelate heavy metal ions such as copper, cadmium, lead, etc. in the soil. While removing heavy metal pollution, it does not react with essential nutrients such as calcium and magnesium for plant growth in the soil, maintaining soil fertility and achieving efficient and green soil remediation, providing strong support for environmental protection.

The chloride ion content of bicine buffer produced by Hubei Xindesheng Material Technology Co., Ltd. is less than 0.1%, and all indicators meet relevant standards. In addition to bicine buffer, Desheng actively researches and develops dozens of biological buffers such as TRIS and hepes commonly used in the market. If you are interested, please click on the Desheng official website to learn more details!

Tags: BICINE buffer, 150-25-4, Biological buffer